Drug Discovery
CH-630
This file is part of the content downloaded from Drug Discovery.
Instructors
Email us if you have any questions!
- Week 1: Prof. Nicola Tirelli (nicola.tirelli@iit.it)
- Week 2: Prof. Andrea Cavalli (andrea.cavalli@epfl.ch)
- Week 3: Dr. Stefania Girotto (stefania.girotto@iit.it)
- Week 4: Alessia Ghidini (alessia.ghidini@epfl.ch)
Introduction
Week 1
- 1.1.1 Introduction to pharmacology (URL)
- 1.1.2 Drug receptor interaction (URL)
- 1.1.3 Drug response (URL)
- 1.2.1 Basic concepts of ADME (URL)
- 1.2.2 More about ADME (URL)
- 1.3.1 Introduction to Pharmacokinetics (URL)
- 1.3.2 Biological barriers and drug delivery (URL)
Week 2
- 2.1.1 Introduction to Drug Discovery (URL)
- 2.2.1 Computational methods in DD (URL)
- 2.2.2 Ligand-based methods and QSAR (URL)
- 2.2.3 Structure-based methods and docking (URL)
- 2.2.4 Virtual screening (URL)
- 2.3.1 Computational binding free energy (URL)
- 2.3.2 Computational residence time (URL)
Week 3
- 3.1.1 Introduction to biophysics in drug discovery (URL)
- 3.2.1 Biophysical approaches and Kinetics of binding (URL)
- 3.2.2 Biophysical approaches and Thermodynamics of binding (URL)
- 3.2.3 Nuclear Magnetic Resonance (NMR) in drug discovery (URL)
- 3.2.4 Ligand-based NMR - From fragment-based screening to binding characterization (URL)
- 3.3.1 Structural biology in drug discovery (URL)