Cellular biology and biochemistry for engineers
BIO-105
This file is part of the content downloaded from Cellular biology and biochemistry for engineers.
This is not the Moddle site for the 2025 edition !!
Please use the link below to go to the 2025 site.
Cellular Biology and Biochemistry for Engineers
Organization of the course :
please watch the video explaining the course organization.
Teaching Assistant:
Ayberk OZKIRLI email : ayberk.ozkirli@epfl.ch
Reference textbooks :
1. Essential Biology (Campbell Reece Simon)
Read on line : use the link provided below.
- Link to the Moodle site for the 2025 class: (Text and media area)
- link to the Moodle site for 2025 (URL)
- * * * * * * * * * * * (Text and media area)
- Link to Essential Biology (3rd) online (URL)
- Essential Biology (7th) Campbell (File)
- 2. Essential Cell Biology (Alberts) (Text and media area)
- Essential Cell Biology (5th) Alberts (File)
- 3. Hilllis Sadava Hill Price Principles of Life (2... (Text and media area)
- chapter 4 (1) (URL)
- ch 4 (2) (URL)
- Ch 4 (3) (URL)
- Ch 4 (4) (URL)
- ch 4 (5) (URL)
- Ch 4 (6) (URL)
- Ch4 (7) (URL)
- link to the Switch channel (URL)
September 21, 2021 (week 1)
Hierarchical organization: atoms, molecules, cells, organisms.
- 2021 welcoming video (URL)
- atomic level: (Text and media area)
- Atomic structure : shell, subshell, orbital (File)
- molecular level: (Text and media area)
- Lecture 1 (Text and media area)
- slides lecture 1-1 (File)
- slides lecture 1-2 (File)
- Exercises : (Text and media area)
September 28, 2021 (week 2)
Plasma membrane, osmosis
- Tuesday 14:15 - 16 :00 : &... (Text and media area)
- Lecture 2 2021 : (Text and media area)
- slides week 2 (2021) (File)
- animated 3D model of bilayer (URL)
- FRAP (URL)
- Hemolysis (File)
- animation : hemolysis (URL)
- 2021 recording 1 in INF-119 (URL)
- 2021 recording 2 in INF-119 (URL)
- Lecture 2 2020 : (recorded) (copy) (Text and media area)
- link to lecture 2 part 1 (URL)
- link to lecture 2 part 2 (URL)
- link to lecture 2 part 3 (URL)
- Exercises : (Text and media area)
- Exercises 1 2021 (File)
October 5th, 2021 (week 3)
Protein in the plasma membrane.
looking for the conformation with the lowest energy level- Lecture 3 (2021) (Text and media area)
- 2021 dias sem 3 (File)
- hydropathy plot (File)
- Lecture 3 (2020) (copy) (Text and media area)
- link to the recorded lecture part 1 (URL)
- link to the recorded lecture part 2 (URL)
- link to lecture 3 part 3 (URL)
- slides week 3 (2020) (File)
- Exercises : (Text and media area)
- Exercises 2 2021 (File)
- link to Seq. Manipulating Suite (URL)
- Link to get random prot. seq. (URL)
- link to generate hydropathy plots (URL)
October 12th, 2021 (week 4)
Resting membrane potential
Energy / Metabolism
mitochondrial ATP synthase
- Lecture 4 (2021) : energy (Text and media area)
- 2021 slides for lecture 4 (Energy) (File)
- recording 1 week 4 2021 (URL)
- recordiing 2 week 4 2021 (URL)
- resting membrane potential animation (File)
- Resting membrane potential (2020) (Text and media area)
- link to the lecture on resting membrane potential (URL)
- simulation ion channels (URL)
- Slides resting membrane potential (File)
- Na+ K+ pump (File)
- resting membrane potential (1) (URL)
- resting membrane potential (from Hillis) (URL)
- Resting Membrane Potential (yvcc) (URL)
- additional, non mandatory tutorials : (Text and media area)
- origin of resting membrane potential (URL)
- link to Introduction to Bioelectricity (MOOC) (URL)
- Lecture 4 (2020) : energy (copy) (Text and media area)
- link to lecture 4 part 1 Energy (URL)
- slides week 4 Energy part 1 (File)
- video on phothosynthesis (detailed) (File)
- Alberts ch 14 Energy (File)
- Animation photosynthesis (File)
- Exercises : (Text and media area)
- exercises 3 BIO-105 2021 (File)
October 19th, 2021 (week 5)
Energy (part 2)
DNA : basics
- Lecture 5 (2021)slides on energy : the last ... (Text and media area)
- 2021 recording 1 week 5 (URL)
- ATP synthase (File)
- 2021 recording 2 week 5 (URL)
- 2021 dias week 5 second hour (File)
- Lecture 5 (2020) (copy) (Text and media area)
- link to video week 5 part 1 (URL)
- slides week 5 ATP synthesis (File)
- link to video week 5 part 2 ATPsynthase (URL)
- exercises : (Text and media area)
- Exercises 4 (week 5) 2021 (File)
October 26th, 2021 (week 6)
DNA Replication
Molecular technics : PCR, microsatellites analysis
- Lecture 6 (2021) (Text and media area)
- 2021 recording 1 week 6 (URL)
- 2021 slides week 6 part 1 (File)
- 2021 recording 2 week 6 (URL)
- 2021 slides week 6 part 2 (File)
- Exercises : (Text and media area)
- 2021 exercises 5 (week 6) (File)
- Probable schedule for the exam (not yet confirmed)... (Text and media area)
- Lecture 6 (2020) (Text and media area)
- link to video 6 part 1 Basics on DNA (URL)
- dias week 6 part 1 (copy) (File)
- link to tutorial 9.1 (URL)
- link to video week 6 part 2 (URL)
- video week 6 part 3 Replication in E. coli (URL)
- Animation replication in E. coli (File)
- video week 6 part 4 (URL)
- animation DNA helicase (File)
- video week 6 part 5 P C R (URL)
- animation : PCR (File)
- slides week 6 P C R (File)
- Hillis : concept 9.2 (replication) (URL)
- Albert's chapter 6 (File)
November 2, 2021 (week 7)
Gene expression : 1 transcription
- Lecture 7 (2021) : (Text and media area)
- 2021 slides for week 7 (File)
- 2021 week 7 recording 1 (URL)
- 2021 week 7 recording 2 (URL)
- Lecture 7 (2020) : (copy) (Text and media area)
- HeLa cells mitosis (File)
- Animation on mitosis (File)
- animation on meiosis (File)
- video lecture 7 part 1 (URL)
- slides lecture 7 part 1 (File)
- video week 7 part 2 (URL)
- slides week 7 part 2 (File)
- Telomere (File)
- Exercises : (Text and media area)
- 2021 Exercises 6 (week 7) (File)
November 9th (week 8)
Gene expression : 2 translation
- Lecture 8 (2021)slides : 2nd part of last week (Text and media area)
- 2021 week 8 recording 1 (URL)
- 2021 week 8 recording 2 (URL)
- Exercises : (Text and media area)
- 2021 Exercises 7 (week 8) (File)
- Lecture 8 (2020) (copy) (Text and media area)
- slides week 8 (2020) (File)
- video week 8 part 1 (transcription) (URL)
- link to tutorial 14.1 (RNApolymerase) (URL)
- video week 8 part 2 (translation) (URL)
- tutorial 14.3 (transcription & translation) (URL)
- translation (eEF-1 correct) (File)
- animation : translation (elongation cycle) (File)
- gene expression (animation) (File)
November 16th (week 9)
Genetics 1 : chromosomes and genes transmission
- Lecture 9 (2021) (Text and media area)
- 2021 slides week 9 (File)
- 2021 week 9 recording 1 (URL)
- 2021 week 9 recording 2 (URL)
- Exercises : (Text and media area)
- 2021 series 8 (week9) (File)
- Lecture 9 (2020) (copy) (Text and media area)
- slides week 9 part 1 (File)
- video week 9 part 1 (URL)
- video week 9 part 2 (URL)
- slides week 9 part 2 (File)
- Exercises : (copy) (Text and media area)
November 23 (week 10)
Genetics 2 :
- Lecture 10 (2021) (Text and media area)
- 2021 recording 2 (week 10) (URL)
- 2021 recording 1 (week 10) (URL)
- 2021 slides week 10 (File)
- animation on meiosis (copy) (File)
- Exercises : (Text and media area)
- 2021 series 9 (week 10) (File)
- Lecture 10 (2020) (Text and media area)
- video lect 10 part 1 autosomal dominant (URL)
- slides week 10 part 1 (File)
- video lecture 10 part 2 (URL)
- slides lect 10 part 2 (File)
- Tutorial on X-linked inheritance (URL)
November 30th (week 11)
1. X inactivation : mutation of XIC
2. genetic distance
- Lecture 11 (2021) (Text and media area)
- 2021 slides week 11 (File)
- 2021 recording 1week 11 (URL)
- Recording for the 2nd hour is not available : plea... (Text and media area)
- video week 11 part 1 (copy) (URL)
- Exercises : (Text and media area)
- 2021 series 10 (week11) (File)
- Lecture 11 (2020) (copy) (Text and media area)
- slides week 11 part 1 (File)
- video week 11 part 1 (URL)
- slides week 11 p2 Genetic distance (File)
- video week 11 p 2 Genetic distance (URL)
December 7th
1. Genetic distance (last slides from last week)
2. Cell to cell communication : paracrine communication
- Lecture 12 (2021) (Text and media area)
- Erratum : corrected version (File)
- 2021 recording 1 week 12 (URL)
- 2021 slides week 12 (File)
- 2021 week 12 recording 2 (URL)
- Exercises : (Text and media area)
- 2021 series 11 (week 12) (File)
- chapter 16 cell signaling (File)
- Lecture 12 (2020) (copy) (Text and media area)
- slides week 12 (2020) (File)
- video week 12 part 1 (URL)
- video week 12 part 2 (URL)
December 14th, 2021
- Lecture 13 2021 : communication part 2 (Text and media area)
- 2021 week 13 recoding 1 (URL)
- 2021 week 13 recoding 2 (URL)
- 2021 time permiting (File)
- explanations on obese yellow mice (URL)
- Exercises : last series = Last Year Exam !!!!!! (Text and media area)
- 2021 exercises 12 (week 13) (File)
- Answers for last year exam (File)
- Lecture 13 2020 : Cancer not covered in 2021 (Text and media area)
- video week 13 p1 (URL)
- slides week 13 p 1 (2020) (File)
- slides wee 13 p2 (2020) (File)
- video week 13 part 2 (URL)
- video week 13 part 3 (URL)
December 21, 2021
Last lecture :
Correction / discussion of last year exam. No new material that may come in the exam, no exercise this week.
- Course 2021 : (Text and media area)
- 2021 week 14 recording 1 (URL)
- 2021 week 14 recording 2 (URL)
- Course 2020 : (copy) (Text and media area)
- 2020 video : informations about the 2020 final exam (URL)
- Compartments & endosymbiosis (File)
Christmas break
January 29 2022, 08:15 - 11:15
EXAM :
room CE 3
Material allowed : 3 A4 paper sheets (= 6 pages). Any content is allowed on these 6 pages : hand written or printed text, formulas, figures, ... .
No other material is allowed : electronic calculators are not allowed.
Remember to have a photo ID available with you and to comply with the COVID regulations.